Synthesis of a Steroidal Conjugate of Methylene Lactone, A Potential Anti-tumour Agent
DOI:
https://doi.org/10.4314/just.v12i2.1031Keywords:
Synthesis, Steroidal methylene lactone, , hormone receptive turnoutsAbstract
A novel steroidal methylene lactone has been synthesized for selectivity of action on hormone receptive tumours such as breast cancer. The design is based on tbc coupling of methylene lactone, a known alkylating agent with established gimmicky, to an estradiol derivative.
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